Multi-scale complex systems approaches for fMRI

🔗📕 Paper: Extracting interpretable signatures of whole-brain dynamics through systematic comparison

tl;dr

For a ~10-minute overview on this topic and project, you might want to check out the recording from my presentation at the Organization for Human Brain Mapping (OHBM) 2024 meeting in Seoul, South Korea, either on YouTube here or below.



Systematically comparing different ways of quantifying dynamical patterns from resting-state fMRI time series

Figure 1 from Bryant et al. (2024): Extracting interpretable signatures of whole-brain dynamics through systematic comparison.

Analysis Aregion: Characterizing localized changes to intra-regional dynamics across disorders

Figure 2 from Bryant et al. (2024): Extracting interpretable signatures of whole-brain dynamics through systematic comparison.

Analysis Afeature: Assessing changes in brain-wide maps of individual dynamical properties across disorders

Analysis Auni_combo: Combining multiple brain regions and temporal properties to represent whole-brain fMRI dynamics across disorders

Analysis AFC: Comparing features of inter-regional functional connectivity across disorders

Figure 3 from Bryant et al. (2024): Extracting interpretable signatures of whole-brain dynamics through systematic comparison.

Analysis AFC_combo: Integrating local regional dynamics with pairwise coupling into one classification model across disorders

Figure 4 from Bryant et al. (2024): Extracting interpretable signatures of whole-brain dynamics through systematic comparison.

Identifying which representation type(s) are optimally suited to capture case–control differences in each disorder

Figure 5 from Bryant et al. (2024): Extracting interpretable signatures of whole-brain dynamics through systematic comparison.